I avoided Adblock for a long time, because I think there's a lot of value in seeing trends in advertising and marketing.
That said, for whatever reason, I've seen a lot of distracting and attention-commanding ads recently, so I made the plunge.
Installed the Adblock Chrome Extension, and ads are now gone.
The verdict?
It's a minor productivity boost, but mostly I'm not noticing them even being gone.
I did set a note on my calendar to turn adblocking back off in a couple months, since I think there is value in seeing how the UI/UX/placement of ads on different sites is evolving, and getting ideas for marketing and sales campaigns.