Last week, I started experimenting with a new setup on the computer and it's working out quite well for me.
I downloaded Mozilla Firefox, which I haven't had installed in a long time (I use a mix of Chrome and Safari). I set up Firefox to have all my primary work materials on it -- Pipeline Deals for CRM/sales, Google Apps for Email, Google Docs (err, Drive) which has our Ops Manual in it, Tout for email tracking... and that's about it. Additional windows for whatever is relevant for research, projects, or client-related stuff.
So far, it's great. When I'm using Chrome (my primary browser), I try to keep the number of tabs down and not overwhelming. That means I might have interesting material loaded up in the tabs that I don't want to close, but also don't want to have open.
Likewise, it's nice to have my work tabs all lined up and logged in without worrying about them taking up mental bandwidth.
Finally, lower procrastination / task-switching, since I know I shouldn't be screwing around in Firefox. It's just for work.
It's pretty early, but it seems like a setup I'll keep. Also, Firefox improved a lot since I last used it a couple years ago. It's just about as fast as Chrome and that brutal memory leak bug seems fixed finally. It might be worth it to create a designated browser for your work if you're doing similar things in similar windows on a daily basis... jury's still out for me, but it looks like a nice little productivity boost for minimal effort so far.